Colorado and Washington became the first U.S. states to legalize the possession and sale of marijuana for recreational use on Tuesday in defiance of federal law, setting the stage for a possible showdown with the Obama administration.

But another ballot measure to remove criminal penalties for personal possession and cultivation of recreational cannabis was defeated in Oregon, where significantly less money and campaign organization was devoted to the cause.

Supporters of a Colorado constitutional amendment legalizing marijuana were the first to declare victory, and opponents conceded defeat, after returns showed the measure garnering nearly 53 percent of the vote versus 47 percent against.

“Colorado will no longer have laws that steer people toward using alcohol, and adults will be free to use marijuana instead if that is what they prefer. And we will be better off as a society because of it,” said Mason Tvert, co-director of the Colorado pro-legalization campaign.

The Drug Policy Alliance, a national advocacy group that backed the initiatives, said the outcome in Washington and Colorado reflected growing national support for liberalized pot laws, citing a Gallup poll last year that found 50 percent of Americans favored making it legal, versus 46 opposed.

Read More:  Chicago Tribune