Health and Human Services Secretary Kathleen Sebelius, who was the face of the president’s health care law, is resigning from the Obama administration, Fox News confirms — a decision that closes one of the rockiest tenures in Obama’s Cabinet.

Sebelius leaves the administration after the tumultuous launch of the Affordable Care Act exchanges last fall. Despite calls for her ouster from Republicans at the time, she stayed on until the enrollment period ended at the end of March.

The administration has since touted the surge in enrollment in the last few weeks, with Sebelius saying Thursday that 7.5 million American have now signed up for coverage under the law.

But the technical difficulties surrounding the launch, as well as ongoing concerns about the implementation of the law, hung over her. She leaves just one week after the enrollment period ended, and as a tough midterm election cycle expected to focus heavily on ObamaCare begins.

Republicans quickly made clear that Sebelius’ departure will not temper their criticisms of ObamaCare.

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