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The U.N. Security Council voted unanimously Friday to secure and destroy Syria’s chemical weapons stockpile.

The vote marked a major breakthrough in the paralysis that has gripped the council since the Syrian uprising began. Russia and China previously vetoed three Western-backed resolutions pressuring President Bashar Assad’s regime to end the violence.

For the first time, the council endorsed the roadmap for a political transition in Syria adopted by key nations in June 2012 and called for an international conference to be convened “as soon as possible” to implement it.

The resolution calls for consequences if Syria fails to comply, but those will depend on the council passing another resolution in the event of non-compliance.

Earlier Friday, President Obama said that a U.N. Security Council resolution requiring Syria to dismantle its chemical-weapons program is “a potentially huge victory for the international community.”

Even though the resolution doesn’t call for the use of force if Syria fails to comply, Mr. Obama said the agreement “represents potentially a significant step forward.”